New York Blood Center (NYBC) is one of the most comprehensive blood centers in the world. Lindsley F. Kimball Research Institute (LFKRI) is the research branch of NYBC. Since its establishment in 1964, LFKRI’s research efforts have paved the way for new blood-related products, techniques and therapies. The Institute’s commitment to ground-breaking research has resulted in numerous landmark patents and licenses.
In my lab, we focus on the role and effector responses of monocytes in healthy individuals and in patients with inflammatory diseases. Circulating monocytes are a heterogeneous and functionally diverse cell population that can be divided into three subsets: classical (CMo), intermediate (IMo), and non-classical monocytes/ patrolling monocytes (PMo). The frequency/number, gene expression profile and activity of IMo and PMo significantly change in a variety of inflammatory diseases including cancer, infectious and autoimmune diseases with the changes associated with disease risk and severity as well as response to treatment. Our ongoing studies examine mechanisms controlling monocyte subset homeostasis and how these mechanisms are altered in inflammatory and disease states. We believe that these studies will not only lead to uncovering new mechanisms for monocyte differentiation and the regulation of inflammation process but also will pave the way for “monocyte diagnostics” and “monocyte therapeutics” in inflammatory diseases.
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We are looking for a highly motivated and organized postdoctoral fellow to provide key scientific support to our on-going monocyte project and we also will support your novel and significant scientific idea to explore new fields. You would be responsible for working with P.I. to design, perform the research work, analyze and interpret data and draft the manuscript.
Ø Designing and performing independent research under the direction of lab Principle Investigator (P.I.)
Ø Performing cell culture, flow cytometry analysis and data analysis.
Ø Processing human samples and isolating various lymphocyte and monocyte subsets.
Ø Processing murine blood and tissue samples.
Ø Managing mouse colonies, including genotyping
Ø Interpreting the experimental data and summarizing timely
Ø Drafting figure and manuscript for publication under the direction of the P.I.
Ø Leading junior research assistants/technicians/students
A doctorate degree (Ph.D. or M.D.) in Immunology, Medicine, Cellular Biology, Molecular Biology or a related field is required. Must have hands-on experience with human cell culture and basic molecular biology laboratory techniques. Superior analytical, trouble-shooting and multi-tasking skills are essential. Prior experience with human primary immune cell culture, complex flow cytometry analysis and mouse handling is preferred. Good laboratory technique, team-work skill, oral/written communication skill are required.
For immediate consideration, please email your CV to: firstname.lastname@example.org
We will provide enough lab space to keep society distance. Masks, gloves and hand sanitizer and other PPE are free to reach with sufficient quantity and excellent quality.